Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endocrine modulation of self- and other-models: A cross-species framework for dyadic social interaction.

Neuroscience and biobehavioral reviews·2026
Same author

Neonatal social communication and single genes predict the variability of post-pubertal social behavior in a mouse model of paternal 15q11-13 duplication.

Research square·2026
Same author

Neonatal social communication and single genes predict the variability of post-pubertal social behavior in a mouse model of paternal 15q11-13 duplication.

bioRxiv : the preprint server for biology·2026
Same author

Dog ownership during adolescence alters the microbiota and improves mental health.

iScience·2026
Same author

Dog temperament is correlated with body weight and climate in country of origin.

Current zoology·2025
Same author

Male mice recognize male-emitted ultrasonic vocalizations in a two-choice test via oxytocin signaling.

Journal of pharmacological sciences·2025

Related Experiment Video

Updated: May 26, 2026

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period
06:40

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period

Published on: April 5, 2024

Dynamic changes in postpartum autonomic nervous system in normal mice: a pilot study.

Kie Shimizu1, Sayaka Kuze-Arata2, Takefumi Kikusui1

  • 1Department of Animal Science and Biotechnology, Azabu University, Sagamihara, Kanagawa, Japan.

Peerj
|May 25, 2026
PubMed
Summary

Maternal autonomic nervous activity changes after childbirth. Healthy mothers show increased heart rate variability post-parturition, unlike those with complications, indicating a potential marker for maternal adaptation.

Keywords:
Autonomic nervous activityDynamic changesElectrocardiogramHeart rate variability analysisLongitudinal studyMouse

More Related Videos

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Related Experiment Videos

Last Updated: May 26, 2026

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period
06:40

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period

Published on: April 5, 2024

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
09:49

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Published on: August 13, 2015

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Area of Science:

  • Physiology
  • Neuroscience
  • Animal Behavior

Background:

  • Female mammalian physiology undergoes significant changes during parturition.
  • Autonomic nervous activity is crucial for normal parturition and maternal well-being.
  • Longitudinal data on autonomic nervous activity around parturition is scarce.

Purpose of the Study:

  • To longitudinally track changes in autonomic nervous activity in mice during the 24 hours surrounding parturition.
  • To compare autonomic nervous activity between mothers experiencing normal parturition and those with abnormal outcomes.
  • To investigate the association between autonomic nervous activity and the transition from pregnancy to lactation.

Main Methods:

  • A longitudinal study using telemetry devices to record electrocardiograms in awake mice.
  • Data collection occurred before, during, and 24 hours after parturition.
  • Time-domain analysis of heart rate variability was used to assess autonomic nervous activity.

Main Results:

  • Normal birthing mice exhibited a significant increase in heart rate variability parameters 24 hours post-parturition.
  • Abnormal birthing mice did not show these increases, with parameters remaining lower than in normal mice.
  • Key parameters included standard deviation of RR intervals, root-mean-square of successive differences, and coefficient of variation of RR intervals.

Conclusions:

  • Autonomic nervous activity dynamics post-parturition are linked to the adaptation from pregnancy to lactation.
  • Distinct patterns of autonomic nervous activity differentiate normal maternal adaptation from parturition complications.
  • Monitoring heart rate variability changes within 24 hours after parturition may help characterize normal maternal states.