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Objective pulse wave amplitude as a potential systemic correlate in childhood myopia: a digital TCM-based study
Fang Sha1,2, Bin Guo1, Dongfang Wang1
1Shandong University of Traditional Chinese Medicine, Jinan, China.
Frontiers in Medicine
|May 25, 2026
Summary
Reduced pulse wave amplitude (h1) is linked to childhood myopia, suggesting systemic factors are involved. Tongue and facial diagnostics did not show significant associations with myopia in children.
Area of Science:
- Ophthalmology
- Integrative Medicine
- Traditional Chinese Medicine (TCM)
Background:
- Childhood myopia is a growing concern with potential systemic influences.
- Traditional Chinese Medicine (TCM) offers a holistic approach to health.
- This study investigates the link between myopia and TCM diagnostic markers.
Purpose of the Study:
- To explore associations between childhood myopia and objective TCM pulse, tongue, and face parameters.
- To identify potential systemic indicators of myopia in children using TCM diagnostics.
Main Methods:
- A cross-sectional study of 873 children (aged 7-14) in China.
- Objective measurements of pulse (h1 amplitude), tongue, and face using digital instruments.
- Myopia defined as cycloplegic spherical equivalent (SE) ≤ -0.50 D; associations analyzed using regression models.
Main Results:
- 53.15% of children had myopia.
- Reduced main pulse wave amplitude (h1) was independently associated with myopia (OR = 0.834, P < 0.001).
- Higher h1 correlated with greater SE and shorter axial length (AL) in older children; no significant tongue/face associations found.
Conclusions:
- Reduced pulse wave amplitude (h1) is a systemic correlate of childhood myopia.
- Objective pulse diagnosis may aid in integrated myopia research.
- Tongue and facial TCM parameters showed no significant association with myopia in this cohort.
