Tele-Electrocardiography and Mortality: Clinical Outcomes in Digital Electrocardiography Cohort-Data from Belo

Gabriela Miana de Mattos Paixão1,2, Carla Paula Moreira Soares1, Paulo Gomes Rodrigues1

  • 1Telehealth Center Hospital das Clínicas of the Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.

Global Heart
|May 25, 2026
PubMed

Insights

Electrocardiogram (ECG) abnormalities significantly increase mortality risk in Brazil. This large cohort study links ECG data to health records, revealing major abnormalities as strong predictors of death and hospitalization.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Cardiovascular diseases are a leading global and Brazilian cause of death.
  • Electrocardiograms (ECGs) are crucial for diagnosing and predicting cardiovascular conditions.

Purpose of the Study:

  • To establish the CODE-BH cohort by linking ECG data with hospitalization and mortality records.
  • To investigate the association between ECG abnormalities and clinical outcomes in a large Brazilian population.

Main Methods:

  • Linked 474,764 ECGs (2006-2018) from 337,021 patients to public health hospitalization and mortality data in Belo Horizonte.
  • Utilized probabilistic linkage methods and a standardized questionnaire for clinical data.
  • Analyzed mortality rates and associated factors, including ECG findings using Minnesota Code.

Main Results:

  • The overall mortality rate was 3.4% over a mean follow-up of 3.3 years.
  • Older age, male sex, comorbidities, and major ECG abnormalities were linked to increased mortality.
  • Any ECG abnormality, particularly major ones, significantly elevated the risk of mortality and cardiovascular hospitalization.

Conclusions:

  • The CODE-BH cohort provides valuable epidemiological data on cardiovascular disease outcomes in Latin America.
  • ECG abnormalities are significant predictors of mortality and cardiovascular hospitalization.
  • This linkage of ECGs to clinical outcomes offers novel insights for public health research and cardiovascular disease management.

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