Related Experiment Video
Updated: May 26, 2026

Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells
Published on: November 21, 2025
Heating Pad-Induced Burns Leading to Rhabdomyolysis and Acute Kidney Injury: Case Report
Meghna Kurup1, Swet Patel1, James Espinosa1
1Emergency Medicine, Jefferson Health NJ, Stratford, USA.
Abstract:
Heating pads are commonly used for pain relief and are generally considered safe; however, prolonged or inappropriate use may result in significant thermal injury. We report the case of a 26-year-old male with a history of psychiatric illness and substance use who presented to the emergency department with deep partial-thickness burns to the back following prolonged heating pad use. Laboratory evaluation revealed severe rhabdomyolysis (creatine kinase 16,823 IU/L) and acute kidney injury (creatinine 11.56 mg/dL), necessitating transfer to a burn center and initiation of renal replacement therapy. Despite involving approximately 10% total body surface area, the burn resulted in significant systemic complications. The patient improved with aggressive fluid resuscitation, dialysis, and surgical management, including grafting, and was discharged after recovery. This case highlights that relatively limited burns from low-intensity heat sources can result in deep tissue injury, rhabdomyolysis, and severe acute kidney injury. Early recognition and prompt management are critical to improving outcomes.
Related Concept Videos
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury V: Interprofessional Care
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury VI: Nursing Management
