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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Narrowing the QRS, Expanding the Function: Left Bundle Branch Pacing in Dilated Cardiomyopathy
Fulvio Cacciapuoti1, Ilaria Caso2, Carlo Liguori3
1Division of Cardiology, "A. Cardarelli" Hospital, Naples, Italy.
Left bundle branch pacing (LBBP) offers a physiological alternative to conventional therapy for heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB). This case study shows LBBP significantly improved symptoms and cardiac function, demonstrating its potential for effective cardiac resynchronization.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Imaging
Background:
- Left bundle branch block (LBBB) causes dyssynchrony in heart failure with reduced ejection fraction (HFrEF), impacting outcomes.
- Conventional cardiac resynchronization therapy has limitations, with up to 30% of patients being non-responders due to nonphysiological activation.
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