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Global trends and advances in pediatric bronchiolitis treatment in the last two decades: a bibliometric analysis
1Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China.
Insights
This bibliometric analysis reveals global trends in pediatric bronchiolitis treatment research. Key areas include respiratory support, RSV therapy, and guidelines, with emerging focus on prevention and infection control.
Area of Science:
- Pediatrics
- Public Health
- Bibliometrics
Background:
- Bronchiolitis is a significant cause of infant morbidity globally.
- This study addresses a gap by analyzing pediatric bronchiolitis treatment trends using bibliometrics.
Purpose of the Study:
- To explore global trends and progress in pediatric bronchiolitis treatment.
- To identify research hotspots and emerging topics in the field.
Main Methods:
- Bibliometric analysis of 1,370 articles published between 2004-2024.
- Literature search conducted in Web of Science Core Collection.
- Data visualization and network analysis using VOSviewer, CiteSpace, and R 'bibliometrix'.
Main Results:
- The United States led publications, followed by China and the UK.
- Key institutions and journals were identified, with notable author contributions.
- Thematic clusters included risk stratification, RSV therapy, respiratory support, guidelines, and clinical trials.
- Emerging topics: epidemiology, prevention, infections, oxygen therapy, and guidelines.
Conclusions:
- Past research focused on optimizing treatment: respiratory support, anti-RSV therapy, and guideline-based care.
- Future research emphasizes prevention, infection control, and high-quality clinical trials for improved outcomes.
Background:
Bronchiolitis, a leading respiratory disease in infants, causes substantial global morbidity. This is the first study to employ bibliometric analysis to explore global trends and progress in pediatric bronchiolitis treatment, addressing a previously unexamined gap.
Methods:
A comprehensive literature search was conducted in the Web of Science Core Collection on January 31, 2025, encompassing publications between 2004 and 2024. The bibliometric analysis utilized VOSviewer, CiteSpace, and the R package "bibliometrix" for data visualization, network analysis, and the identification of research hotspots.
Results:
A total of 1,370 articles were included in this study. The United States emerged as the leading contributor with 403 articles, followed by China [101] and the United Kingdom [79]. The most prolific institutions included Assistance Publique-Hôpitaux de Paris and Harvard University. Notable journals such as Pediatrics and Pediatric Pulmonology were identified as key platforms for high-impact authors, with prominent figures such as Babl Franz E. making substantial contributions to the field. Keyword analysis indicated five thematic clusters, including risk stratification-based therapy, anti-respiratory syncytial virus therapy, respiratory support, clinical-practice guideline, and clinical trials. Emerging topics included "epidemiology", "prevention", "infections", "oxygen therapy", and "guideline", which were more prominently featured in recent years.
Conclusions:
Research on pediatric bronchiolitis over the past 20 years has focused on optimizing treatment, particularly respiratory support, anti-respiratory syncytial virus therapy, and guideline-based care. Emerging trends emphasize prevention, infection control, and high-quality clinical trials to improve patient outcomes.
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