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Updated: May 26, 2026

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates
Published on: October 3, 2017
Illuminating consciousness
Conor H Murray1, Kafui Dzirasa2,3,4, Dana Sawyer5
1Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
Abstract:
What consciousness is, and how it relates to the body and nature at large, are among the most enduring questions in human history. Notable thinkers have long grappled with its definition, mechanisms, and purpose. In this review, we examine both historical and contemporary perspectives on consciousness across philosophy, science, medicine, and practice. By integrating diverse perspectives and lines of evidence, from neuroscientific models to clinical applications and contemplative methods, we aim to synthesize insights into a more holistic framework of consciousness. Our objective is two-fold: first, to identify common themes and persistent gaps in knowledge, and second, to highlight critical opportunities for future investigation. In doing so, we advance a working model of consciousness that considers how consciousness is constructed, how it can be measured and modified, and why it may be central not only to survival, but also to human flourishing.
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