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The Maxwell Finland Lecture 2025: Antimicrobial Resistance At The Bedside: Translating Science Into Patient Outcomes
Cesar A Arias1,2,3
1Charles W. Duncan Jr. Department of Medicine, Division of Infectious Diseases, Houston Methodist Hospital, Houston, TX, USA.
The Journal of Infectious Diseases
|May 26, 2026
Summary
Antimicrobial resistance (AMR) is a major global health threat driven by microbial evolution. Dr. Maxwell Finland
Area of Science:
- Microbiology
- Public Health
- Infectious Diseases
Background:
- Antimicrobial resistance (AMR) poses a significant 21st-century public health challenge.
- Microbial evolution is a primary driver of AMR, diminishing antibiotic effectiveness.
- The rise of AMR threatens modern medicine, which relies heavily on antibiotics.
Purpose of the Study:
- To highlight the critical and growing threat of antimicrobial resistance (AMR).
- To underscore the importance of understanding microbial evolution in the context of AMR.
- To emphasize the enduring relevance of Dr. Maxwell Finland's pioneering work in infectious diseases and antimicrobial therapies.
Main Methods:
- Historical review of antimicrobial development and the emergence of resistance.
- Analysis of the role of microbial adaptation in challenging infectious disease treatment.
- Examination of Dr. Maxwell Finland's contributions to the field of infectious diseases.
Main Results:
- Antimicrobial resistance is escalating, rendering previously effective antibiotics less potent.
- Microorganisms' capacity for rapid evolution is a key factor fueling AMR.
- Dr. Finland's research provides foundational insights into the dynamics of antimicrobial use and resistance.
Conclusions:
- The increasing prevalence of AMR necessitates urgent global attention and innovative solutions.
- Understanding microbial evolution is crucial for combating antimicrobial resistance.
- Dr. Maxwell Finland's legacy serves as a vital reference point for addressing contemporary challenges in infectious diseases and antimicrobial stewardship.
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