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Related Concept Videos

Tandem Mass Spectrometry01:21

Tandem Mass Spectrometry

Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then passed on to...
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
Atomic Absorption Spectroscopy: Atomization Methods01:25

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Atomic Absorption Spectroscopy (AAS) atomizes samples through flame atomization or electrothermal atomization. Flame atomization typically involves a nebulizer and spray chamber assembly to combine the sample with a fuel–oxidant mixture, creating a fine aerosol mist that enters a burner. Typically, the fuel and oxidant are combined in an approximately stoichiometric ratio. However, for atoms that are easily oxidized, a fuel-rich mixture may be more advantageous. Only about 5% of the aerosol...
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Inductively coupled plasma (ICP) is the most widely used plasma source in atomic emission spectroscopy (AES), also known as Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The ICP source, or torch, consists of three concentric quartz tubes with argon gas flowing through them. A spark from a Tesla coil initiates the ionization of argon, generating a high-temperature plasma.
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
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PTR-ToF-MS Coupled with an Automated Sampling System and Tailored Data Analysis for Food Studies: Bioprocess Monitoring, Screening and Nose-space Analysis
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Integrated Aerosol Collection and Thermal-Desorption Chemical Ionization TOFMS for Rapid Particulate-Composition

Zhenming Wang1, Jichuang Kong1, Ruidong Liu1

  • 1Environment Research Institute, Shandong University, 72 Binhai Road, Qingdao 266237, China.

Analytical Chemistry
|May 26, 2026
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Summary

A new method, AeroCT-TOFMS, rapidly analyzes organophosphate esters in particulate matter. This technology enhances collection rates and signal detection, offering a promising tool for air quality monitoring.

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Published on: March 3, 2017

Area of Science:

  • Environmental Chemistry
  • Analytical Chemistry
  • Atmospheric Science

Background:

  • Particulate matter (PM) organic molecules oxidize, altering atmospheric composition and impacting health and visibility.
  • Effective online monitoring of these changes, especially for specific compounds like alkyl organophosphate esters (alkyl-OPEs), is challenging.

Purpose of the Study:

  • To develop and validate a novel integrated aerosol collection and thermal-desorption chemical ionization time-of-flight mass spectrometry (AeroCT-TOFMS) system.
  • To enable rapid, quantitative analysis of alkyl-OPEs from packaging materials in express delivery stations (EDS).

Main Methods:

  • An integrated system combining aerosol collection and thermal-desorption mass spectrometry on a bidirectional motion platform.
  • A dual-heating strategy (350 °C radiation, 110 °C air) for rapid desorption (within 50 s) of PM components.
  • Quantitative analysis of alkyl-OPEs with a linear range of 0.1-20 ng and a limit of detection of 0.016 ng.

Main Results:

  • AeroCT-TOFMS demonstrated a 22.2% higher collection rate and up to 204.8% enhanced signal for triethyl phosphate (TEP) compared to FIGAERO.
  • Analysis of EDS samples revealed TEP concentrations of 0.43-1.61 ng/m³ and tributyl phosphate concentrations of 1.28-1.81 ng/m³ after 60 min collection.
  • The system provides rapid, quantitative insights into particulate alkyl-OPEs.

Conclusions:

  • The novel AeroCT-TOFMS system offers a significant advancement for rapid, online quantitative analysis of particulate alkyl-OPEs.
  • This technology has broad application prospects for monitoring air quality and chemical composition in various environments.
  • The system addresses the limitations of current online monitoring approaches for atmospheric particulate organic compounds.