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Testing a Smartphone-Based Intervention Targeting Anxiety Sensitivity Among Women Presenting for Emergency Care After
Nicole A Short1, Regine Deguzman-Lucero1, Rachel Weese1
1Department of Psychology, University of Nevada, Las Vegas, Mail Stop: 5030 4505 S. Maryland Pkwy, Las Vegas, NV, 89154, United States, 1 7028950606.
JMIR Formative Research
|May 26, 2026
Summary
Smartphone interventions targeting anxiety sensitivity (AS) show promise for reducing PTSD symptoms in sexual assault survivors. This pilot study found significant reductions in AS and PTSD symptoms by 6 months, supporting feasibility and acceptability.
Area of Science:
- Mental Health
- Trauma Recovery
- Digital Therapeutics
Background:
- Anxiety sensitivity (AS) is a key target for reducing posttraumatic stress disorder (PTSD) after trauma.
- Smartphone interventions for AS show potential acceptability and efficacy in sexual assault survivors.
- Previous studies were limited to small, one-arm proof-of-concept designs.
Purpose of the Study:
- To conduct a pilot randomized controlled trial (RCT) of a smartphone-based AS intervention.
- To evaluate intervention efficacy, changes in AS and PTSD symptoms.
- To assess intervention acceptability, credibility, and feasibility for a larger RCT.
Main Methods:
- 60 women with high AS post-sexual assault were recruited from emergency care.
- Participants were randomized to an AS intervention or a control condition.
- Follow-up occurred for 6 months using remote self-report questionnaires.
Main Results:
- High rates of probable PTSD were observed at 7 weeks and 6 months post-assault.
- The AS intervention was rated as acceptable by a majority of completers.
- Statistically significant reductions in AS and PTSD symptoms were observed by 6 months in both groups.
- Recruitment and retention data supported study design feasibility.
Conclusions:
- A smartphone-based intervention targeting AS is feasible and acceptable for sexual assault survivors.
- Significant reductions in AS and PTSD symptoms were achieved by 6 months.
- Further research is needed to optimize intervention and assessment compliance.

