Related Experiment Video
Updated: May 27, 2026

Mixed Reality Assisted Radical Endoscopic Thyroidectomy
Published on: January 31, 2025
Trauma-Induced Thyroid Storm After Road Traffic Accident Polytrauma
Alya Elmaimona H Abdelmageed1, Malaz S Younis2,3, Sahar Alomar4,5
1Emergency Department, Omdurman Military Hospital, Khartoum, SDN.
Abstract:
Thyroid storm (TS) is a rare, life-threatening exacerbation of hyperthyroidism, where the thyroid gland produces too much of the thyroid hormones, often triggered by causes such as infection or surgery. Although rare, trauma can precipitate the transition from thyrotoxicosis to TS. Though typically seen in patients with known hyperthyroidism - especially Graves' disease - the onset of TS can be unpredictable and rapidly fatal if not promptly addressed. We present a 20-year-old male who developed TS following a road traffic accident. On arrival, the patient was in hypovolemic shock and subsequently underwent an emergency laparotomy and splenectomy for a grade V splenic injury. Despite intensive care unit (ICU) support, the patient showed persistent tachycardia, high fever (40.8°C), and reduced Glasgow Coma Scale (GCS). Thyroid function tests (TFT) confirmed biochemical thyrotoxicosis. This case highlights trauma as an uncommon but significant precipitant of TS, especially in patients unaware of underlying thyroid disease. Diagnostic delays may occur as symptoms mimic common post-trauma complications. In trauma patients with unexplained systemic instability, TS should be considered since early recognition and targeted treatment are vital to reduce morbidity and mortality.
Related Concept Videos
Hyperthyroidism II: Pathophysiology
Hyperthyroidism I: Introduction
Graves Disease II: Pathophysiology
Graves' Disease I: Introduction
Hypothyroidism II: Pathophysiology
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
