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Related Concept Videos

CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

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CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its effects by...
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An Overview of Psychoactive Drugs

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Altered States of Awareness01:06

Altered States of Awareness

Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
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Hallucinogens and Psychedelics

Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
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Sedatives and Hypnotics Drugs: Miscellaneous Agents

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Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
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Published on: February 5, 2018

[New psychoactive substances].

Dorte Fris Palmqvist1, Ragnar Thomsen2, Brian Schou Rasmussen2

  • 1Anæstesiologisk Afdeling, Københavns Universitetshospital - Bispebjerg og Frederiksberg Hospital.

Ugeskrift for Laeger
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PubMed
Summary
This summary is machine-generated.

New psychoactive substances (NPS) pose a growing public health risk due to their increasing availability and varied potency. Monitoring these unregulated drugs is crucial for public safety and clinical guidance.

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Area of Science:

  • Pharmacology
  • Toxicology
  • Public Health

Background:

  • New psychoactive substances (NPS) are unregulated drugs that present a significant public health challenge.
  • The recreational market sees a continuous rise in the diversity and availability of NPS.
  • NPS encompass a wide range of substances, including sedatives, opioids, stimulants, hallucinogens, dissociatives, and cannabinoids.

Purpose of the Study:

  • To review the classification and characteristics of NPS.
  • To highlight the public health threat posed by NPS.
  • To emphasize the importance of NPS monitoring for legislation, exposure reduction, and clinical practice.

Main Methods:

  • Literature review of NPS classification and trends.
  • Analysis of NPS pharmacological properties and market presence.
  • Discussion of clinical implications and monitoring strategies.

Main Results:

  • NPS are categorized into six main pharmacological groups.
  • Ease of access, variable potency, and novel compositions characterize NPS.
  • Clinicians often lack experience in managing NPS-related intoxications.

Conclusions:

  • Effective monitoring of NPS is essential for timely legislative updates.
  • Monitoring NPS helps in reducing public exposure and guiding clinical management.
  • A comprehensive approach to NPS is needed to address the evolving public health threat.