Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 28, 2026

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

DNA Origami and Their Application in Biosensors.

Iqra Nosheen Salim1, Rebecca Reay1, Christine Denby2

  • 1School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, 3 Byrom way, Liverpool L3 3AF, UK.

Biosensors
|May 26, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modelled impact of a multi-cancer early detection screening programme on cancer treatment in England.

British journal of cancer·2026
Same author

Molecular imprinting of aptamer/carbamazepine complexes for the development of an optical nanosensor.

The Analyst·2026
Same author

Real-world outcomes following adjuvant chemotherapy for resected pancreatic cancer in a centralised oncology service.

British journal of cancer·2026
Same author

Development and validation of a diagnostic prediction model for pancreatic ductal adenocarcinoma: VAPOR 1, protocol for a prospective multicentre case-control study.

BMJ open·2025
Same author

Comparing the trends of MBS telepsychiatry and consultant physician telehealth services from 2017 to 2022: A retrospective study-CORRIGENDUM.

Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists·2025
Same author

European Registry of Hereditary Pancreatic Diseases (EUROPAC): protocol for primary and secondary screening in individuals with inherited pancreatic disease syndromes for pancreatic ductal adenocarcinoma and complications of other pancreatic diseases.

BMJ open·2025

DNA origami enhances biosensors for precise, real-time detection of diverse targets. Future work aims to improve stability and biocompatibility for clinical applications.

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Biosensors have advanced from basic electrochemical devices to sophisticated tools incorporating AI for multiplex detection.
  • DNA origami integration offers enhanced precision, programmability, and recognition capabilities for biosensing systems.

Purpose of the Study:

  • To systematically review the integration of DNA origami with various biosensor platforms.
  • To explore the design approaches for DNA origami nanostructures in biosensing.
  • To highlight the potential and challenges of DNA origami-based biosensors.

Main Methods:

  • Literature review of studies incorporating DNA origami with fluorescence, SERS, SPR, and electrochemical biosensors.
  • Analysis of DNA origami nanostructure design strategies for biosensing applications.
Keywords:
DNA nanostructuresDNA origamibiosensorsdesign toolsdiagnostics

More Related Videos

Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

Related Experiment Videos

Last Updated: May 28, 2026

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
08:59

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications

Published on: September 27, 2019

Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

Main Results:

  • DNA origami-based biosensors demonstrate high sensitivity, precise spatial control, and rapid, modular detection.
  • These biosensors can detect targets ranging from small molecules to large biological species.
  • Versatile applications are identified across multiple sectors.

Conclusions:

  • DNA origami significantly boosts biosensor performance, enabling precise and versatile molecular detection.
  • Key challenges such as reproducibility and stability need addressing for clinical translation.
  • Future research should focus on enhancing biocompatibility and structural integrity for point-of-care diagnostics.