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The Landscape of Genetically Driven Immune Disorders
Xiao P Peng1, Jo L Wilson2, Dusan Bogunovic3,4
1New York Center for Rare Diseases, Division of Pediatric Genetic Medicine, Department of Pediatrics, Montefiore Medical Center and Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
Abstract:
AbstractThe increasingly widespread use of genetic diagnostic testing has shed light on genetic architectures, landscapes, and paradigms corresponding to the clinical and immune features of genetically driven immune disorders, but this wealth of information has also contributed additional layers of complexity for patient diagnosis and care. This review discusses concepts related to genetically driven immune disorders as they apply to current diagnostic and management strategies to help clinicians navigate these complexities.
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