Related Experiment Video
Updated: May 28, 2026

08:47
Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
Risk of Edentulism Among Older Adults with Multimorbidity.
1Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London WC2R 2LS, UK.
Dentistry Journal
|May 26, 2026
Summary
Older American adults with multiple chronic conditions face a higher risk of complete tooth loss. This highlights the importance of oral health promotion for individuals with multimorbidity.
Area of Science:
- Gerontology
- Public Health
- Dental Epidemiology
Background:
- Multimorbidity, the presence of multiple chronic conditions, is common in older adults.
- Complete tooth loss (edentulism) significantly impacts quality of life and overall health in the elderly population.
- Understanding the longitudinal relationship between multimorbidity and edentulism is crucial for targeted health interventions.
Purpose of the Study:
- To investigate the association between multimorbidity and the incidence of complete tooth loss among older American adults.
- To examine the role of socioeconomic factors and behavioral factors in this relationship.
Main Methods:
- Utilized longitudinal data from three waves of the Health and Retirement Study (HRS).
- Assessed multimorbidity based on five chronic conditions (diabetes, heart conditions, lung diseases, cancer, stroke) in 2012.
- Employed Structural Equation Modelling (SEM) to analyze the relationship between 2012 multimorbidity and edentulism in 2018, excluding participants with prior tooth loss.
Main Results:
- Each additional chronic condition was associated with a 1.30 times higher odds of edentulism.
- SEM confirmed a positive association between multimorbidity and edentulism.
- Smoking and lower wealth were significantly associated with both multimorbidity and edentulism.
Conclusions:
- Older adults with multimorbidity demonstrate an increased probability of becoming edentate.
- These findings underscore the necessity of integrating oral health promotion into care strategies for individuals with multiple chronic conditions.
- Public health initiatives should address the interconnectedness of systemic health, socioeconomic factors, and oral health outcomes in aging populations.
Related Concept Videos
Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Pharmacodynamics in Geriatric Patients: Effects of Age
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...