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Ventricular-Arterial Coupling in Takotsubo Syndrome: Controversies and Opportunities
1Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Insights
This review details hemodynamic assessments for Takotsubo syndrome (TTS) patients, including blood pressure and cardiac output. It highlights their importance in managing TTS and understanding its pathophysiology.
Area of Science:
- Cardiology
- Cardiovascular Physiology
Background:
- Takotsubo syndrome (TTS) presents diagnostic challenges.
- Hemodynamic parameters are crucial for understanding TTS pathophysiology and management.
- Existing literature shows discrepancies in key hemodynamic measurements.
Abstract:
The present review focuses on the particulars of the hemodynamic assessment of patients with Takotsubo syndrome (TTS), i.e., blood pressure, cardiac output, systemic vascular resistance, left ventricular ejection fraction, left ventricular-arterial coupling (VAC), left ventricular end-diastolic pressure (LVEDP), and their importance in the management of patients with TTS, and the unraveling of its pathophysiology. In addition, the review discusses the discrepancies noted in the reported literature on the LVEDP and the left VAC, speculating as to the underlying reasons, and providing recommendations.
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