Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Volume and Density of Epicardial Adipose Tissue Measured by Computed Tomography as Markers of the Effects of Cardiovascular Disease Risk Factors.

Journal of cardiovascular development and disease·2026
Same author

Who will keep patients safe? The largest multi-centre survey of healthcare students exposes critical gaps in radiation safety education.

BMC medical education·2026
Same author

Coronary Computed Tomography Angiography as a Method for Diagnosing a Thrombotic Occlusion of a Giant Right Coronary Artery Aneurysm in a Patient with Difficulty in Visualizing the Right Coronary Artery During Invasive Coronary Angiography.

Diagnostics (Basel, Switzerland)·2026
Same author

The Relationship Between Meal Composition and the Body Composition of Wroclaw Medical University Students.

Nutrients·2026
Same author

Individualized Radiation Dose Assessment in Low-Dose Chest CT: The Role of DLPss and Topogram Optimization.

Journal of clinical medicine·2026
Same author

Ultrasound-Assessed Brachial Artery Flow-Mediated Dilation and Carotid Plaque Burden as Markers of Vascular Health in Relation to Weekly Physical Activity Duration in Older Adults.

Diagnostics (Basel, Switzerland)·2026

Related Experiment Video

Updated: May 28, 2026

Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice
05:08

Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice

Published on: October 3, 2019

Well-Known and Novel Behavioural Risk Factors for Heart Failure.

Natalia Kusyn1,2, Natalia Zdebik1, Wojciech Hajdusianek1

  • 1Department of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, Mikulicza-Radeckiego 7, 50-345 Wrocław, Poland.

Journal of Cardiovascular Development and Disease
|May 26, 2026
PubMed
Summary
This summary is machine-generated.

Lifestyle choices like smoking, poor diet, and inactivity significantly impact heart failure (HF) risk and progression. Understanding these behavioral factors and their mechanisms is key for preventing HF and guiding future research.

Keywords:
behavioural HF risk factorsheart failure (HF)heart failure risk factors

Related Experiment Videos

Last Updated: May 28, 2026

Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice
05:08

Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice

Published on: October 3, 2019

Area of Science:

  • Cardiology
  • Public Health
  • Preventive Medicine

Background:

  • Heart failure (HF) affects millions globally, with ischemic heart disease as a primary cause.
  • Behavioral and lifestyle factors play a crucial role in HF onset and progression.
  • Established and emerging risk factors require comprehensive review.

Purpose of the Study:

  • To review established and novel behavioral risk factors for heart failure.
  • To explore the underlying pathophysiological mechanisms of these risk factors.
  • To identify targets for primary prevention and future research directions.

Main Methods:

  • Literature review of epidemiological data and pathophysiological insights.
  • Focus on established risk factors: smoking, alcohol, obesity, inactivity, diet, sleep disorders, stress.
  • Inclusion of novel determinants: electronic nicotine delivery systems (ENDS), cannabis, caffeine, psychostimulants.

Main Results:

  • Behavioral factors significantly influence HF development and worsening.
  • Mechanisms include endothelial dysfunction, oxidative stress, neurohormonal activation, and myocardial toxicity.
  • Evidence supports a link between various lifestyle choices and HF.

Conclusions:

  • Behavioral factors are critical targets for heart failure primary prevention.
  • Further research is needed to elucidate mechanisms and refine preventive strategies.
  • Integrating epidemiological and pathophysiological data is essential for combating HF.