Incidence and Predictive Factors for Surgical Interventions Following Simple Congenital Heart Disease Interventional...

Area of Science:

• Cardiology
• Interventional Cardiology
• Pediatric Cardiology

Background:

• Interventional occlusion for congenital heart disease (CHD) can lead to complications requiring reintervention.
• Predictive factors for these reinterventions remain largely undefined.
• Understanding these factors is crucial for improving patient outcomes.

Purpose of the Study:

• To comprehensively analyze the occurrence rates of severe post-interventional occlusion complications.
• To identify independent predictive factors for reintervention in patients with simple CHD.
• To provide a reference for optimizing CHD treatment strategies.

Main Methods:

• Retrospective case-control study of 4190 patients with simple CHD undergoing transcatheter/interventional procedures (2017-2022).
• Monitoring of perioperative and postoperative complications at 1, 3, and 6 months.
• Statistical analysis of clinical, ultrasound, and laboratory data for 44 patients requiring reintervention.

Main Results:

• For atrial septal defects (ASD), defect size and age grading were independent predictors.
• For ventricular septal defects (VSD), predictors included occluder size, aortic annulus diameter, body surface area, and defect isolation.
• Receiver operating characteristic (ROC) curve analysis showed moderate predictive ability for identified factors.

Conclusions:

• This study presents the first comprehensive analysis of reintervention predictors after CHD occlusion.
• Identified factors offer new insights for managing complications in ASD and VSD.
• Findings serve as a valuable reference for interventional cardiologists treating CHD.