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Recurrent Pericarditis in a Middle-Aged Female with MEFV Mutation
Xiaohang Liu1,2, Tongxin Xiao2,3, Lihua Zhang1
1Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100006, China.
Recurrent pericarditis can be challenging in TB-endemic areas. Genetic analysis revealed an autoinflammatory cause in a patient, shifting focus from infection to inflammation for better treatment.
Area of Science:
- Cardiology
- Genetics
- Rheumatology
Background:
- Recurrent pericarditis (RP) presents diagnostic challenges, particularly in tuberculosis (TB)-endemic regions.
- Empirical anti-TB therapy is often prolonged unnecessarily in these settings.
- A case of a 35-year-old woman with three RP episodes over six months is presented.
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