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Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
Research Progress on Marine Active Substances in Improving Atherosclerosis
Chenyang Xie1,2, Jiapeng Qi2,3, Wenmei Huang4
1Engineering Technological Center of Mushroom Industry, School of Biological Science and Biotechnology, Minnan Normal University, Zhangzhou 363000, China.
Abstract:
Atherosclerosis is the primary pathological foundation of various cardiovascular and cerebrovascular diseases. Although existing treatment strategies exhibit certain efficacy, they still encounter limitations such as pronounced side effects and a single-target approach. The oceans have nurtured a rich diversity of organisms, and the secondary metabolites they generate possess novel structures, diverse activities, and unique mechanisms of action, offering new prospects for the development of anti-atherosclerotic drugs. This paper reviews advancements related to research on marine-derived active substances that possess anti-atherosclerotic activity, as well as current challenges in research on active substances, with the objective of laying a foundation for the development of anti-atherosclerotic drugs.
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