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Updated: May 28, 2026

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

Published on: July 31, 2017

Adaptive Behavior Change in Autism: Outcomes from a Comprehensive, Interdisciplinary Clinical Care Cohort.

Kelly Olvany¹, Annie Aitken^1,2, Elysa J Marco¹

¹Cortica Healthcare, San Diego, CA 92121, USA.

Journal of Personalized Medicine

|May 26, 2026

Summary

Children with Autism Spectrum Disorder (ASD) showed improved adaptive behavior skills with the Cortica interdisciplinary model. This medically centered approach led to greater growth compared to a community sample.

Keywords:

adaptive behaviors autism growth curves treatment models

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Area of Science:

Neuroscience
Developmental Psychology
Pediatric Medicine

Background:

Autism Spectrum Disorder (ASD) presents challenges in adaptive behavior.
Interdisciplinary treatment models are increasingly explored for ASD interventions.
Measuring changes in adaptive behavior is crucial for assessing intervention efficacy.

Purpose of the Study:

To evaluate the impact of the medically centered, interdisciplinary Cortica treatment model on adaptive behavior in children with ASD.
To compare the longitudinal changes in adaptive behavior for children receiving Cortica care versus a community sample.
To investigate the effectiveness of a comprehensive program integrating behavioral, developmental, and medical oversight.

Main Methods:

Longitudinal analysis of Vineland Adaptive Behavior Scales (VABS) data.
Comparison between children in the Cortica program and a matched community sample from the National Database for Autism Research (NDAR).
Application of propensity score weighting and multilevel growth curve modeling to control for baseline differences.

Main Results:

Significant Cohort × Time interactions were observed for the Adaptive Behavior Composite (ABC) score and all VABS subscales.
Children in the Cortica cohort demonstrated significantly greater growth in adaptive behavior skills over time compared to the NDAR cohort.
The findings indicate a positive effect of the Cortica model on the development of adaptive behaviors.

Conclusions:

The study underscores the value of adaptive behaviors as a key outcome measure in ASD clinical research.
A personalized, multidisciplinary intervention approach, like the Cortica model, can significantly enhance adaptive behavior skills in children with ASD.
These findings support the efficacy of integrated care models in improving functional outcomes for individuals with ASD.