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Updated: May 28, 2026

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
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Genomic Medicine Among Ophthalmologists: Knowledge, Current Practice, and Barriers.

Walaa Bakhamees1,2, Hend Alsafran1,3, Hani Basher ALBalawi4

  • 1Vitreoretinal and Uveitis Division, King Khaled Eye Specialist Hospital, Riyadh 11462, Saudi Arabia.

Journal of Personalized Medicine
|May 26, 2026
PubMed
Summary

Ophthalmologists in Saudi Arabia recognize the value of genomic medicine and genetic testing, but knowledge gaps persist. Integrating genetics into ophthalmology education is crucial for advancing precision medicine in the region.

Keywords:
attitudegenomic medicineknowledgeophthalmologistspractices

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Area of Science:

  • Ophthalmology
  • Genomic Medicine
  • Precision Medicine

Background:

  • Genomic medicine and genetic testing are increasingly vital in ophthalmology.
  • Saudi Arabia is transitioning towards precision medicine.
  • Assessing current ophthalmologist knowledge, attitudes, and practices is essential.

Purpose of the Study:

  • To evaluate Saudi Arabian ophthalmologists' knowledge, attitudes, and practices regarding genomic medicine and genetic testing.
  • To identify gaps in understanding and confidence in genetic testing applications.
  • To inform curriculum development for genetics in ophthalmology.

Main Methods:

  • A cross-sectional survey was distributed to ophthalmologists across Saudi Arabia.
  • The questionnaire covered demographics, knowledge of genomics, confidence in genetic tasks, and attitudes toward genetic testing.
  • Data were analyzed using descriptive and inferential statistics.

Main Results:

  • 115 ophthalmologists participated, showing variable knowledge (e.g., high on inheritance patterns, low on DNA base-pairing).
  • Confidence was highest in referrals and lowest in test selection/counseling.
  • Most ophthalmologists held positive attitudes towards genetic testing but noted access difficulties and privacy concerns.

Conclusions:

  • Saudi ophthalmologists acknowledge the importance of genetics in their field.
  • Significant gaps in knowledge and familiarity with genomic medicine require attention.
  • Integrating genetics into ophthalmology curricula is recommended to address these challenges.