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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
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Breeding by Design for Functional Rice with Genome Editing Technologies
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Application of Gene Editing Technology in Poultry.

Ruyu Liao1, Rong Ran1, Yixin Liu1

  • 1College of Animal Science and Technology, Southwest University, Chongqing 400715, China.

Veterinary Sciences
|May 26, 2026
PubMed
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Gene editing technologies like CRISPR/Cas9 offer precise genetic modifications for agricultural animals. This review covers advancements, applications in poultry, and future challenges in animal husbandry.

Keywords:
CRISPR/Cas9animal breedingdelivery vectorgene editingpoultry animals

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Area of Science:

  • Molecular Biology
  • Genetics
  • Animal Science

Background:

  • Gene editing allows precise genomic modifications for desired traits.
  • CRISPR/Cas9 is the dominant gene editing tool in agricultural animals since 2014.
  • Newer systems like base and prime editors offer improved precision and safety.

Purpose of the Study:

  • To review the development of gene editing technologies.
  • To discuss the advantages and limitations of key gene editing tools.
  • To explore gene editing applications in poultry and animal husbandry.

Main Methods:

  • Literature review of gene editing technologies.
  • Analysis of CRISPR/Cas9, base editors, and prime editors.
  • Examination of gene editing applications in poultry and livestock.

Main Results:

  • Gene editing enhances production traits and disease resistance in animals.
  • Applications include disease detection and creating disease models.
  • Advancements facilitate transition from lab research to practical applications.

Conclusions:

  • Gene editing holds significant potential for animal husbandry.
  • Challenges include off-target effects, ethical considerations, and technical complexities.
  • Future prospects depend on addressing these challenges for safe and effective implementation.