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Published on: January 3, 2025
Application of Gene Editing Technology in Poultry
Ruyu Liao1, Rong Ran1, Yixin Liu1
1College of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Veterinary Sciences
|May 26, 2026
Summary
Gene editing technologies like CRISPR/Cas9 offer precise genetic modifications for agricultural animals. This review covers advancements, applications in poultry, and future challenges in animal husbandry.
Area of Science:
- Molecular Biology
- Genetics
- Animal Science
Background:
- Gene editing allows precise genomic modifications for desired traits.
- CRISPR/Cas9 is the dominant gene editing tool in agricultural animals since 2014.
- Newer systems like base and prime editors offer improved precision and safety.
Purpose of the Study:
- To review the development of gene editing technologies.
- To discuss the advantages and limitations of key gene editing tools.
- To explore gene editing applications in poultry and animal husbandry.
Main Methods:
- Literature review of gene editing technologies.
- Analysis of CRISPR/Cas9, base editors, and prime editors.
- Examination of gene editing applications in poultry and livestock.
Main Results:
- Gene editing enhances production traits and disease resistance in animals.
- Applications include disease detection and creating disease models.
- Advancements facilitate transition from lab research to practical applications.
Conclusions:
- Gene editing holds significant potential for animal husbandry.
- Challenges include off-target effects, ethical considerations, and technical complexities.
- Future prospects depend on addressing these challenges for safe and effective implementation.
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