Related Experiment Video
Updated: May 28, 2026

04:08
Metacarpal Small Incision for Carpal Tunnel Syndrome
Published on: April 5, 2024
Thumb Carpometacarpal Joint Denervation Has Lower Reoperation Rates Than Trapeziectomy for Thumb Base Arthritis: A
Julian Wier1, Daniel Rusu1, Aidan Lindgren1
1Department of Orthopaedic Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
The Journal of Hand Surgery
|May 26, 2026
Summary
Carpometacarpal (CMC) denervation showed significantly lower reoperation rates than trapeziectomy for CMC osteoarthritis at 2 years. This suggests denervation may offer short- to mid-term benefits before more invasive surgeries.
Area of Science:
- Orthopedic Surgery
- Hand Surgery
- Musculoskeletal Disorders
Background:
- Thumb carpometacarpal (CMC) osteoarthritis is a common condition.
- Surgical options include trapeziectomy and CMC denervation.
- Limited comparative data exists on the long-term efficacy of these procedures.
Purpose of the Study:
- To compare the rates of secondary surgery after trapeziectomy versus CMC denervation for CMC osteoarthritis.
- To investigate the relative longevity of these two surgical interventions.
Main Methods:
- Retrospective query of the PearlDiver Mariner Database for patients with CMC arthritis.
- Propensity score-matched analysis comparing CMC denervation and trapeziectomy cohorts.
- Primary endpoint: all-cause reoperation rates at 2 years, excluding hardware removal.
Main Results:
- 540 patients in each matched cohort (denervation vs. trapeziectomy).
- Cohorts were well-balanced in age, comorbidity, and sex.
- Denervation group had significantly lower reoperation rates (3.3% vs. 7.8%, P=.002) at 2 years.
Conclusions:
- CMC denervation was associated with significantly lower reoperation rates compared to trapeziectomy at the 2-year follow-up.
- Integrating CMC denervation earlier in treatment algorithms may provide short- to mid-term benefits.
- Further research is needed to validate these findings and assess long-term outcomes.
