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Multidomain correlates of burnout: A population-based study using supervised machine learning
Anja Monstadt1,2, Yvonne Friedrich3, Fabian Rottstädt3,4
1Department of Clinical Psychology, Friedrich-Schiller-Universität Jena, Jena, Germany. anja.monstadt@uni-jena.de.
Social Psychiatry and Psychiatric Epidemiology
|May 26, 2026
Summary
Burnout is significantly predicted by poor work-life balance and mental health issues like depression and anxiety. Positive work environments may prevent burnout, while existing mental health problems increase vulnerability.
Area of Science:
- Occupational Health
- Psychology
- Sociology
Background:
- Burnout is a significant occupational health concern with increasing societal impact.
- Understanding burnout risk factors is crucial for developing effective prevention strategies.
Purpose of the Study:
- To investigate the relationship between burnout and organizational factors, psychosocial employment conditions, sociodemographic variables, and mental health.
- To identify key predictors of burnout severity using advanced machine learning techniques.
Main Methods:
- Analysis of cross-sectional survey data from the German population-based DigiHero cohort (n=27,020).
- Utilized linear associations and XGBoost machine learning to explore multidomain variable relationships with burnout, measured by the Maslach Burnout Inventory.
- Interpreted machine learning results using SHAP values and compared with univariate statistics, adjusting for sample bias.
Main Results:
- Effort-reward imbalance, work-life interference, overcommitment, and poor general mental health (depression, anxiety symptoms) were the strongest burnout predictors.
- Psychosocial employment conditions and individual mental health were more influential than organizational and sociodemographic factors.
- Occupation, extended remote work, age, and income showed smaller but notable effects on burnout.
Conclusions:
- Psychosocial employment conditions and individual mental health are paramount in burnout etiology, overshadowing organizational and sociodemographic factors.
- Positive social work environments are suggested for burnout prevention, while pre-existing mental health issues heighten vulnerability.
- Prospective longitudinal studies are recommended for deeper causal insights into burnout development.
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