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Published on: July 14, 2023
Diabetic peripheral neuropathy in type 2 diabetes: prevalence and associated factors in Midwest Brazil
Lorrany Campos de Queiroz Melo1, Gleyson Souza da Costa2, Matheus Eduardo Soares2
1Programa de Pós-graduação em Biociências e Saúde, Universidade Federal de Rondonópolis, Rondonópolis, MT, Brasil.
Objective:
This study investigated the prevalence and factors associated with diabetic peripheral neuropathy (DPN) among adults with type 2 diabetes mellitus (T2DM) attending a referral center in Midwest Brazil.
Subjects And Methods:
This cross-sectional study included 276 patients with T2DM, categorized into DPN and non-DPN groups. DPN was assessed using the Neuropathy Disability Score. Sociodemographic and lifestyle data were collected via structured interviews, whereas clinical and laboratory data were obtained from medical records.
Results:
DPN prevalence was 64.5% (95% CI: 58.9%-70.1%). Among those affected, most were female (59.0%), aged over 67 years old (37.7%), living with diabetes for more than 10 years (52.3%). Poor glycemic control and a sedentary lifestyle were observed in 78.9% and 85.4% of participants, respectively. In multivariable analysis, male sex (PR = 1.32; 95% CI: 1.12-1.56), retirement/inactivity (PR = 1.43; 95% CI: 1.11-1.85), T2DM duration >10 years (PR = 1.22; 95% CI: 1.03-1.44), sedentary lifestyle (PR = 1.34; 95% CI: 1.02-1.76), peripheral arterial disease (PR = 1.25; 95% CI: 1.08-1.46), and prior acute myocardial infarction (PR = 1.21; 95% CI: 1.01-1.45) were independently associated with higher DPN prevalence.
Conclusion:
DPN was highly prevalent among patients with T2DM. Particular attention should be directed toward men, older adults, individuals with long-standing diabetes, and those with cardiovascular comorbidities. Promoting regular physical activity and comprehensive management of cardiovascular risk factors may help prevent disease progression and related complications.
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