Related Experiment Video
Updated: May 28, 2026
A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat
Published on: October 6, 2018
Needle to scalpel: Navigating the path from SIRVA to surgical intervention
Lori McGowan1, Danielle O'Laughlin, Brittany Strelow
1At Mayo Clinic in Rochester, MN, Lori McGowan is supervisor of advanced practice providers (APPs) in the Division of Orthopedic Surgery, APP education specialist for orthopedic surgery, supervisor of the integrated community specialties orthopedic and podiatry teams, and lead preceptor in orthopedics. She also serves on the Mayo Clinic NPPA Education Subcommittee for Rochester, Florida, and Arizona. Danielle O'Laughlin is an assistant professor, PA, and team lead of the primary care gynecology clinic in the Division of Community Internal Medicine, Geriatrics, and Palliative Care at Mayo Clinic. She also serves as co-director of clinical skills in the Mayo PA program and serves on the NPPA Research Committee. Brittany Strelow is an assistant professor of medicine in the Division of Community Internal Medicine, Geriatrics, and Palliative Care at Mayo Clinic. She also serves as adjunct faculty for Augsburg University, Butler University, and Northeastern University. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Shoulder injury related to vaccine administration (SIRVA) can cause persistent pain and limited mobility. This case highlights diagnostic challenges and surgery as a potential treatment for refractory SIRVA cases.
Area of Science:
- Medical Science
- Immunology
- Orthopedic Surgery
Background:
- Shoulder injury related to vaccine administration (SIRVA) is a rare but debilitating condition.
- Improper vaccine injection can lead to various shoulder injuries and inflammatory responses.
Purpose of the Study:
- To illustrate the diagnostic challenges of SIRVA.
- To highlight surgery as a management option for refractory SIRVA cases.
Main Methods:
- Focused clinical history collection.
- Thorough physical examination.
- Case presentation of a patient with refractory SIRVA.
Main Results:
- SIRVA diagnosis can be challenging, leading to delayed treatment.
- Patients may exhaust nonoperative treatments before considering surgery.
- Limited literature exists on surgical management of SIRVA.
Conclusions:
- Timely diagnosis and effective management are crucial for mitigating SIRVA complications.
- Surgery may be a viable option for unusually refractory SIRVA cases, despite limited existing literature.
