Related Experiment Video

Updated: May 28, 2026

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines
08:42

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines

Published on: July 19, 2019

Global Cancer Prevention: Current Approaches and Future Directions

Clement A Adebamowo1, Karen Canfell2, Sally N Adebamowo1

  • 1Department of Epidemiology and Public Health, and the Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD.

American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting
|May 26, 2026
PubMed

Insights

Preventable cancer interventions, targeting risk factors like tobacco and infections such as human papillomavirus (HPV), are underutilized globally. Implementing policy, financing, and research is crucial for reducing cancer incidence and mortality, especially in high-need areas.

Area of Science:

  • Global oncology
  • Cancer epidemiology
  • Preventive medicine

Background:

  • Cancer represents a significant and escalating global health challenge, with millions of new cases and deaths annually.
  • A substantial proportion of cancer cases are preventable by addressing modifiable risk factors such as tobacco use, obesity, alcohol consumption, and infections like human papillomavirus (HPV).
  • Despite proven effectiveness, primary cancer prevention strategies are not fully implemented worldwide.

Purpose of the Study:

  • To synthesize the global burden of preventable cancers.
  • To review progress and challenges in cervical cancer elimination via HPV vaccination, screening, and treatment.
  • To examine cancer control strategies in Africa, highlighting areas with high preventable cancer fractions.

Main Methods:

  • Quantification of preventable cancer burden using population attributable fractions.
  • Synthesis of data from the 2026 ASCO Annual Meeting Education Session on global cancer prevention.
  • Review of evidence-based approaches for cancer control and elimination strategies.

Main Results:

  • The global burden of preventable cancers is substantial, with significant variations across regions.
  • Progress in cervical cancer elimination is noted, but challenges remain in widespread HPV vaccination, screening, and treatment.
  • Cancer control approaches in Africa show potential, with a high preventable fraction of cancer burden.

Conclusions:

  • Translating existing prevention evidence into practice requires coordinated policy, financing, workforce development, and research.
  • Priority actions are needed to reduce cancer incidence and mortality, particularly in resource-limited settings.
  • Enhanced global efforts in primary cancer prevention are essential to mitigate the growing cancer burden.

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...