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Updated: May 28, 2026

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines

Published on: July 19, 2019

Global Cancer Prevention: Current Approaches and Future Directions.

Clement A Adebamowo¹, Karen Canfell², Sally N Adebamowo¹

¹Department of Epidemiology and Public Health, and the Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD.

American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting

|May 26, 2026

Summary

This summary is machine-generated.

Preventable cancer interventions, targeting risk factors like tobacco and infections such as human papillomavirus (HPV), are underutilized globally. Implementing policy, financing, and research is crucial for reducing cancer incidence and mortality, especially in high-need areas.

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Last Updated: May 28, 2026

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines

Published on: July 19, 2019

Area of Science:

Global oncology
Cancer epidemiology
Preventive medicine

Background:

Cancer represents a significant and escalating global health challenge, with millions of new cases and deaths annually.
A substantial proportion of cancer cases are preventable by addressing modifiable risk factors such as tobacco use, obesity, alcohol consumption, and infections like human papillomavirus (HPV).
Despite proven effectiveness, primary cancer prevention strategies are not fully implemented worldwide.

Purpose of the Study:

To synthesize the global burden of preventable cancers.
To review progress and challenges in cervical cancer elimination via HPV vaccination, screening, and treatment.
To examine cancer control strategies in Africa, highlighting areas with high preventable cancer fractions.

Main Methods:

Quantification of preventable cancer burden using population attributable fractions.
Synthesis of data from the 2026 ASCO Annual Meeting Education Session on global cancer prevention.
Review of evidence-based approaches for cancer control and elimination strategies.

Main Results:

The global burden of preventable cancers is substantial, with significant variations across regions.
Progress in cervical cancer elimination is noted, but challenges remain in widespread HPV vaccination, screening, and treatment.
Cancer control approaches in Africa show potential, with a high preventable fraction of cancer burden.

Conclusions:

Translating existing prevention evidence into practice requires coordinated policy, financing, workforce development, and research.
Priority actions are needed to reduce cancer incidence and mortality, particularly in resource-limited settings.
Enhanced global efforts in primary cancer prevention are essential to mitigate the growing cancer burden.