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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Sub-Ultraviolet Reflectance and Ultraviolet-induced Fluorescence Dermatoscopy in Action: Shedding Light on a Case of

Julien Anriot1,2, Nadia Ikhlef2, Arnaud De La Fouchardière3,4

  • 1Claude Bernard Lyon-1 University, LyonFrance.

Dermatology Practical & Conceptual
|May 26, 2026
PubMed
Abstract

No abstract available in PubMed .

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...

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