Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction model and novel classification system for complications after minimally invasive hysterectomy.

Gynecologic and obstetric investigation·2026
Same author

Risk factors for postoperative opioid prescription after benign hysterectomy.

European journal of obstetrics & gynecology and reproductive biology: X·2026
Same author

An attempt to improve recognition of fetal acidemia by a remodeled intrapartum cardiotocography classification: A case-control study.

Acta obstetricia et gynecologica Scandinavica·2026
Same author

Academic achievement in children born extremely preterm: a cohort study.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same author

Vaginal Hysterectomy Versus Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery Hysterectomy; Results of a Randomised Controlled Trial.

BJOG : an international journal of obstetrics and gynaecology·2026
Same author

Analysis of Prevalence and Mortality Among Neonates and Children With Intestinal Atresia: A Multinational Study, 1974-2015.

Birth defects research·2026

Related Experiment Video

Updated: May 28, 2026

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
10:31

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

ADNOLA trial: a study-protocol - a randomised controlled trial study comparing adnexal surgery by vNOTES or

Kristin Stuhr Olsson1,2, Jan Filip Baekelandt3,4, Karin Källén5

  • 1Institute of Clinical Sciences, Department of Obstetrics and Gynecology, Lund University, Lund, Sweden kristin.s.olsson@skane.se.

BMJ Open
|May 26, 2026
PubMed
Summary

This study will compare vaginal natural orifice transluminal endoscopic surgery (vNOTES) with conventional laparoscopy in women undergoing adnexal surgery. It aims to determine which method offers better outcomes, focusing on postoperative pain.

Keywords:
Minimally invasive surgeryRandomized Controlled TrialSURGERY

More Related Videos

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
11:29

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma

Published on: January 22, 2022

Related Experiment Videos

Last Updated: May 28, 2026

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
10:31

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
03:07

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial

Published on: August 19, 2025

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
11:29

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma

Published on: January 22, 2022

Area of Science:

  • Minimally invasive gynecologic surgery
  • Surgical innovation
  • Endoscopic procedures

Background:

  • Adnexal surgery is a common procedure in women.
  • Minimally invasive techniques reduce surgical morbidity compared to abdominal surgery.
  • Vaginal natural orifice transluminal endoscopic surgery (vNOTES) is an emerging innovation combining vaginal and endoscopic approaches.

Purpose of the Study:

  • To compare outcomes between vNOTES and conventional laparoscopy for adnexal surgery.
  • To evaluate postoperative pain as the primary outcome.
  • To assess secondary outcomes including analgesic use and complications.

Main Methods:

  • A multicentre pragmatic randomised controlled trial (RCT) involving 200 women aged 18+ undergoing adnexal surgery.
  • Randomization to either vNOTES or laparoscopy groups.
  • Recruitment from Q4 2025 to 2028, with primary outcome of postoperative pain.

Main Results:

  • Postoperative pain is the primary outcome measure.
  • Secondary outcomes include analgesic consumption, perioperative complications, operation time, and readmission rates.
  • Surgeon experience will also be evaluated.

Conclusions:

  • This pragmatic RCT will provide crucial data on the efficacy and safety of vNOTES compared to laparoscopy.
  • Findings will inform clinical practice regarding the adoption of vNOTES for adnexal surgery.
  • The study addresses the current lack of large-scale comparative trials.