[Predictive factors for in-hospital death after acute coronary syndrome: Data from REACTIV registry 2019 to 2023]

H Yao1, S N'Zonzy1, A Ekou1

  • 1Institut de cardiologie d'Abidjan, 01 BP V 206, Abidjan, Côte d'Ivoire.

Annales De Cardiologie Et D'Angeiologie
|May 26, 2026
PubMed

Insights

Acute coronary syndromes (ACS) in Abidjan are linked to significant in-hospital death. Key risk factors include age, diabetes, and severe heart rhythm disorders, while percutaneous coronary intervention (PCI) offers protection.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Acute coronary syndromes (ACS) represent a growing clinical challenge in Abidjan.
  • Understanding in-hospital mortality predictors is crucial for improving patient outcomes.

Purpose of the Study:

  • To identify factors predicting in-hospital death among patients with ACS at the Abidjan Heart Institute.
  • To analyze trends in ACS prevalence and mortality over a five-year period.

Main Methods:

  • An observational prospective study was conducted from January 2019 to December 2023.
  • Data from 661 ACS patients admitted to the Intensive Care Unit (ICU) were analyzed.
  • Multivariate analysis identified significant risk and protective factors for in-hospital mortality.

Main Results:

  • ACS prevalence was 20.0% among ICU admissions, affecting a median age of 57 years with male predominance.
  • Major cardiovascular risk factors included hypertension (55.6%), active smoking (33.4%), and diabetes (25.7%).
  • In-hospital mortality was 9.5%, with age, diabetes, Killip class ≥2, and severe ventricular rhythm disorders identified as risk factors. Percutaneous coronary intervention (PCI) was protective (RR 0.4).

Conclusions:

  • ACS is associated with substantial in-hospital mortality in Abidjan, with identifiable risk factors.
  • Percutaneous coronary intervention (PCI) demonstrates a significant protective effect against in-hospital death.
  • Developing ACS management networks and enhancing technical facilities are recommended to improve long-term outcomes.
Abstract

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...