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Updated: May 28, 2026
07:30
Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
CAA or not? When cerebral microbleeds are not enough.
Marialuisa Zedde1, Rosario Pascarella2
1Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, Reggio Emilia, 42123, Italy. marialuisa.zedde@gmail.com.
Summary
Cerebral microbleeds (CMBs) can indicate cerebral amyloid angiopathy (CAA), but this case highlights radiation therapy as a potential cause. Careful differential diagnosis is crucial, especially with a history of whole brain radiotherapy (WBRT).
Area of Science:
- Neurology
- Radiology
- Oncology
Background:
- Lobar cerebral microbleeds (CMBs) are key indicators of cerebral amyloid angiopathy (CAA).
- Small vessel disease (SVD) markers like white matter hyperintensities (WMHs) and enlarged perivascular spaces (EPVSs) are increasingly recognized.
- Current diagnostic frameworks may not fully encompass the implications of multiple SVD markers.
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