Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Do ADHD Symptom Clusters Moderate the Association Between Autistic Traits & Error-Related Negativity in Children With and Without Autism?: An EEG/ERP Study.

Journal of autism and developmental disorders·2026

Same author

Acoustic analyses of the RAVDESS corpus of emotional stimuli.

JASA express letters·2026

Same author

The Developmental Approach to Autism Science: Considering Cognitive Ability in the Age of Neuroimaging Research.

Developmental psychobiology·2025

Same author

A cascading effects model of early sensory development in autism.

Psychological review·2025

Same author

Cicchetti's organizational-developmental perspective of Down syndrome: Contributions to the emergence of developmental psychopathology and the study of persons with neurodevelopmental conditions.

Development and psychopathology·2024

Same author

Examining the latent structure and correlates of sensory reactivity in autism: a multi-site integrative data analysis by the autism sensory research consortium.

Molecular autism·2023

Search research articles

Related Experiment Video

Updated: May 28, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Linking Auditory Brainstem Neural Stability to Parent-Reported Autistic Traits in School-Age Children.

Devon Pacheco Major¹, Emily Cary², Erin Matsuba²

¹Department of Communication Sciences and Disorders, Syracuse University, 621 Skytop Rd. Suite 1200, Syracuse, NY 13244, USA.

|May 27, 2026

Summary

Neural stability in the auditory brainstem is linked to autistic traits. Specifically, less stable neural responses correlate with higher scores on the Autism Spectrum Quotient (AQ), but not the Social Responsiveness Scale (SRS-2).

Keywords:

auditory brainstem response autism electrophysiology neural stability

More Related Videos

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Published on: October 3, 2018

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

Published on: July 31, 2017

Related Experiment Videos

Last Updated: May 28, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism

Published on: October 3, 2018

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research

Published on: July 31, 2017

Area of Science:

Neuroscience
Auditory Processing
Developmental Disorders

Background:

Neural stability, or consistency in brain responses to stimuli, is crucial for processing information.
The auditory brainstem response (ABR) offers an electrophysiological method to assess neural stability.
Previous research on neural stability in autism spectrum disorder (ASD) has yielded inconsistent findings.

Purpose of the Study:

To investigate the link between auditory brainstem neural stability and autistic traits in children.
To determine if neural stability varies with stimulus type and ABR component.
To explore the relationship between neural stability and parent-reported autistic traits using the AQ and SRS-2.

Main Methods:

Auditory brainstem responses (ABRs) were recorded in children with and without autism.
Neural stability was quantified by analyzing trial-to-trial variability in ABR waveforms.
Parent-reported autistic traits were assessed using the Autism Spectrum Quotient (AQ) and the Social Responsiveness Scale-2 (SRS-2).

Main Results:

Neural stability differed across ABR components, with click ABRs showing greater stability than sABRs.
Reduced neural stability was significantly associated with higher scores on the AQ, indicating a link with broader autistic traits.
No significant association was found between neural stability and SRS-2 scores.

Conclusions:

Auditory brainstem neural stability is related to individual differences in autistic traits, particularly those measured by the AQ.
These findings suggest that early sensory processing stability may be associated with broader autistic features, not solely social communication deficits.