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Oridonin Suppresses Colorectal Cancer Growth In Vitro and In Vivo: Evidence from Integrated Transcriptomic and

Menglong Xu1, Yongchao Li1, Wenqiang Sun1

  • 1Department of Biochemistry and Molecular Biology, College of Life Science and Technology, the State Key Laboratory Incubation Base for Conservation and Utilization of Bio-Resource in the Tarim Basin of the Xinjiang Production and Construction Corps, Tarim University, Alar 843300, China.

Current Issues in Molecular Biology
|May 27, 2026
PubMed
Summary

Oridonin (ORI) effectively suppresses colorectal cancer (CRC) growth by regulating cell cycle progression and apoptosis. This natural compound shows promise as a potential therapeutic agent for advanced CRC.

Keywords:
apoptosiscolorectal canceroridoninproteomictranscriptomic

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