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Updated: May 28, 2026
10:42
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
Published on: February 27, 2019
Antioxidant, Anti-Inflammatory and Anticancer Peptides from Extreme Marine Environments
Muhammad Zakariya1, Eleonora Montuori1, Gwendoline Kopp1
1Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via A.F. Acton 55, 80133 Napoli, Italy.
Antioxidants (Basel, Switzerland)
|May 27, 2026
Summary
Marine peptides from extreme environments offer unique therapeutic potential. Research highlights anticancer, antioxidant, and anti-inflammatory properties, emphasizing the need for advanced exploration technologies.
Area of Science:
- Marine natural products
- Bioprospecting
- Peptide therapeutics
Background:
- Marine organisms are rich sources of bioactive compounds.
- Seventeen marine-derived molecules are approved for human diseases, primarily cancer.
- Peptides are highly promising candidates for therapeutic applications.
Purpose of the Study:
- To review peptides from marine organisms in extreme environments (deep ocean, polar, tropical).
- To highlight the unique biomolecules and stability profiles evolved under extreme conditions.
- To discuss the potential for bioprospecting novel therapeutic agents.
Main Methods:
- Literature review of marine-derived peptides.
- Analysis of reported bioactivities (anticancer, antioxidant, anti-inflammatory).
- Examination of peptides from deep-sea, polar, and tropical marine ecosystems.
Main Results:
- Deep-sea environments yielded eight anticancer peptides.
- Polar habitats provided nine antioxidant, two anti-inflammatory, and seven anticancer peptides.
- Tropical waters yielded approximately ninety peptides, including antioxidant, anti-inflammatory, and anticancer agents.
Conclusions:
- Marine peptides from extreme environments possess significant therapeutic potential.
- Unique stability profiles enhance efficacy and shelf-life for industrial applications.
- Future research requires advanced technologies for sampling, cultivation, and efficacy assessment in extreme environments.
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