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Surgical Decision-Making in Breast Cancer: A Retrospective Comparative Study from a Tertiary Center.
Florin Bobirca1,2, Dan Dumitrescu1,2, Florentina Gherghiceanu3
1Surgery Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Journal of Clinical Medicine
|May 27, 2026
Summary
This study compared breast-conserving surgery (BCS) with modified radical mastectomy in 101 breast cancer patients. Mastectomy was more frequent, and significant differences in hemoglobin levels were observed between the groups.
Area of Science:
- Oncology
- Surgical Oncology
- Clinical Research
Background:
- Breast cancer treatment involves surgical options like breast-conserving surgery (BCS) and mastectomy.
- Comparing clinical-paraclinical parameters between these surgical approaches is crucial for optimizing patient outcomes.
Purpose of the Study:
- Determine the frequency of BCS versus modified radical mastectomy.
- Compare clinical-paraclinical parameters between patients undergoing BCS and mastectomy.
Main Methods:
- Observational, retrospective study design.
- Included 101 breast cancer patients with surgical interventions between January 2024 and April 2025.
- Analysis of clinical-paraclinical data, including hemoglobin levels.
Main Results:
- Breast-conserving surgery (BCS) was performed in 36.6% of cases; modified radical mastectomy in 63.4%.
- A statistically significant difference in admission hemoglobin levels was noted between the BCS and mastectomy groups (13.7 g/dL vs. 12.7 g/dL, p=0.010).
Conclusions:
- Surgical technique selection for breast tumors remains an active area of research in surgical specialties.
- Factors like disease stage, histopathological subtype, and surgeon preference influence surgical choice.
- Oncological outcomes may be comparable across different surgical approaches, warranting further investigation.
