Molecular Structure Regulation of Polyacrylamide-Based Drag Reducers on Solubility and Transient Gel-Layer Behavior:...

This study aimed to clarify how molecular structure regulates the dissolution and transient gel-layer behavior of polyacrylamide-based dry-powder drag reducers for slickwater fracturing. In the Materials Studio 2020 software, molecular dynamics simulations were performed on five representative homopolymers, including: polyacrylamide (PAM), polyacrylic acid (PAA), poly(2-acrylamido-2-methylpropane sulfonic acid) (PAMPS), poly(N-vinylpyrrolidone) (PNVP), and poly [2-(acryloyloxy)ethyl]trimethylammonium chloride (PDAC). The results show that in pure water, PAA exhibits the strongest thermodynamic driving force with an interaction energy of -1005.5 kcal/mol and the lowest solvation free energy of -373.289 kcal/mol. Quantitative correlation analysis established that solvation energy and hydrogen bond density are primary predictors of macroscopic performance, yielding a correlation coefficient of R² > 0.94. Experiments confirm that optimized AM/AA (7:3) and AM/AMPS (5:5) anionic copolymers achieve stable viscosity within 120 ± 5 s and 160 ± 8 s, respectively, representing a 60% reduction in dissolution time compared to conventional industrial PAM homopolymers. The polarity, charge density, and chain flexibility of functional groups jointly regulate polymer dissolution behavior. Anionic groups significantly improve dissolution performance by enhancing intramolecular electrostatic repulsion and hydration.