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Updated: May 28, 2026

Breeding by Design for Functional Rice with Genome Editing Technologies
Published on: January 3, 2025
Applications of Gene-Editing Technologies in Enhancing Crop Stress Resistance with Emphasis on Rice.
Minghui Sun1,2, Fozia Ghouri1,2, Muhammad Waqas3
1State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, South China Agricultural University, Guangzhou 510642, China.
Gene editing, particularly CRISPR/Cas9, enhances crop resilience to biotic and abiotic stresses, offering solutions for global food security. Further optimization promises highly adapted, high-yielding crop varieties for sustainable agriculture.
Area of Science:
- Agricultural Science
- Biotechnology
- Genetics
Background:
- Gene editing offers innovative strategies for crop stress management.
- CRISPR/Cas9 is a key tool for enhancing resistance to biotic and abiotic stresses.
- Challenges include off-target effects and complex gene interactions.
Purpose of the Study:
- To review gene-editing applications in crop stress research.
- To examine the impact of various stresses on crops.
- To provide guidance for developing stress-tolerant crop varieties.
Main Methods:
- Review of gene-editing technologies, focusing on CRISPR/Cas9.
- Analysis of gene functions related to stress resistance in crops, especially rice.
- Discussion of strategies to overcome gene editing limitations.
Main Results:
- Gene editing has successfully developed stress-resistant crop varieties.
- CRISPR/Cas9 effectively modifies genes for drought, salinity, temperature, and disease resistance.
- Optimized gene editing can lead to highly resilient and high-yielding crops.
Conclusions:
- Gene editing is crucial for developing crops adapted to complex environments.
- It significantly contributes to sustainable agriculture and global food security.
- Further integration with other technologies will enhance crop stress tolerance.
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