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Cellulose and Its Derivatives-Based Skin Dressings: Design, Smart Advances and Applications
Shiyan Wang1, Yu Wang1, Mengran Guo1
1Department of Pharmacy, West China Hospital, Sichuan University, Chengdu 610041, China.
Pharmaceutics
|May 27, 2026
Summary
Cellulose materials offer promising solutions for skin diseases, including wound healing and infection control. Their adaptable forms and smart responsive systems enhance therapeutic outcomes and enable wearable monitoring.
Area of Science:
- Biomaterials Science
- Dermatology
- Regenerative Medicine
Background:
- Skin disease treatment presents ongoing clinical challenges.
- Cellulose and its derivatives are increasingly researched for skin applications due to biocompatibility and modifiability.
- Diverse cellulose-based material formats (films, scaffolds, hydrogels, aerogels) are being explored.
Purpose of the Study:
- To systematically review cellulose-based materials for skin applications.
- To focus on smart responsive systems for microenvironmental conditions.
- To analyze mechanisms and applications in skin disease therapy and wearable devices.
Main Methods:
- Systematic review of literature on cellulose-based materials.
- Analysis of material forms: films, nanofibrous scaffolds, hydrogels, aerogels.
- Examination of smart responsive systems and their mechanisms.
Main Results:
- Cellulose materials show progress in wound healing, infection management, burn treatment, scar prevention, and immunomodulation.
- Smart responsive cellulose systems are tailored for specific microenvironmental conditions.
- Applications extend to smart wearable monitoring devices.
Conclusions:
- Cellulose-based materials are versatile for treating various skin conditions.
- Understanding mechanisms like anti-infection and pro-regeneration is key for development.
- Future research can leverage these materials for advanced skin therapies and smart wearables.
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