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Updated: May 28, 2026

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
Published on: July 12, 2024
From Environmental Concentrations to Individual Inhalation: Analysis of Exposure Differences to PM2.5 and Chemical
Ruoyu Li1,2, Fenghua Lin3, Hao Zhang3
1Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou 350108, China.
Abstract:
(1) Background: This study investigated the characteristics and influencing factors of exposure to fine particulate matter (PM2.5) and its chemical composition among elderly residents, with the aim of revealing potential differences in exposure. (2) Methods: A total of 258 elderly individuals were monitored for 72 h through individual, indoor, and outdoor PM2.5 measurements. Concentrations were determined, and non-targeted components were analyzed by gas chromatography-mass spectrometry (GC-MS). Through Spearman correlation analysis, generalized linear model, and linear regression to explore the influencing factors. (3) Results: The individual PM2.5 concentration was higher than both the indoor and outdoor concentrations. A total of 20,962 compounds were detected in personal PM2.5 samples, 6794 in indoor PM2.5 samples, among which 4285 compounds were shared between the two sample types. The components were mainly esters, aromatic compounds, and amines. PM2.5 concentration was correlated with age, housing area, humidifier use, and second-hand smoke exposure. Chemical composition is related to outdoor pollution, furniture material, and daily behavior. (4) Conclusions: The individual PM2.5 concentration is higher than the environmental concentration, and its chemical composition overlaps with the indoor and outdoor environment, which is jointly affected by demography, living conditions, and daily behavior.
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