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Antimicrobial Resistance in Veterinary Bacterial Pathogens: Resistance Patterns, Zoonotic Risks and One Health
Ionela Popa1,2, Ionica Iancu3, Sebastian Alexandru Popa4
1Department of Semiology, Faculty of Veterinary Medicine, University of Life Sciences "King Mihai I" from Timisoara, 300645 Timisoara, Romania.
Antimicrobial resistance (AMR) is a major global health threat in both human and animal medicine. Addressing AMR requires integrated monitoring and stewardship programs to control resistant bacteria and mobile genetic elements.
Area of Science:
- Veterinary Medicine
- Public Health
- Genomics
Background:
- Antimicrobial resistance (AMR) is a critical global health issue impacting human and veterinary medicine.
- Resistant bacterial strains in animals pose risks of zoonotic transmission and treatment failure.
- Widespread resistance genes necessitate integrated monitoring systems.
Purpose of the Study:
- To highlight the significance of AMR in veterinary medicine.
- To emphasize the need for integrated monitoring and stewardship.
- To discuss the role of mobile genetic elements in AMR spread.
Main Methods:
- Review of molecular and genomic studies on AMR.
- Analysis of resistance gene dissemination.
- Examination of mobile genetic elements.
Main Results:
- Prevalence of resistant bacterial strains in livestock and companion animals is increasing.
- Resistance genes are widespread across ecological compartments.
- Multidrug-resistant (MDR) pathogens are linked to mobile genetic elements.
Conclusions:
- Integrated monitoring systems are essential for combating AMR.
- Antimicrobial stewardship programs are crucial in veterinary practice.
- Understanding horizontal gene transfer is key to mitigating AMR spread.
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