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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...

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Articles linked to this work by shared authors, journal, and citation graph.

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Kratom Cutaneous Hyperpigmentation: An Emerging Dermatosis for Dermatopathologists and Dermatologists to Recognize.

Journal of cutaneous pathology·2026
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The National Resident Match Program Arrives in Dermatopathology: 15 Years of Resilient Advocacy by the American Society of Dermatopathology's Fellowship Training Program Directors' Committee.

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Unusual neon pink color change in a radiotherapy tattoo.

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Pregnancy Associated Atypical Onychopapilloma: A Novel Presentation of an Emerging Entity in Dermatopathology.

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Novel Histopathologic Features of Median Canaliform Dystrophy.

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Novel Use of Nail Surgical Instruments for Grossing of Nail Pathology Specimens: Improving Specimen Quality and Safety for Laboratory Staff.

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Related Experiment Video

Updated: May 28, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Bowenoid Malignant Onychopapilloma.

Kendall Billick1, Carli Tucci2, Erika Koh3

  • 1Division of Dermatology, Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada.

Journal of Cutaneous Pathology
|May 27, 2026
PubMed
Summary

Malignant onychopapilloma (OP), a rare cancer of the nail unit, can present with Bowenoid features. This case highlights a unique histopathologic pattern expanding the spectrum of malignant nail tumors.

Area of Science:

  • Dermatopathology
  • Oncology
  • Nail Unit Neoplasms

Background:

  • Onychopapilloma (OP) is a nail unit tumor typically presenting as longitudinal erythronychia.
Keywords:
Bowenoidmalignant onychopapillomanail histopathology

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  • Historically considered benign, rare malignant variants of OP have been reported.
  • These malignant variants retain the OP architectural scaffold but show cytologic atypia.