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First Comprehensive Global Bibliometric Analysis of Monkeypox Virus Research Landscape From 1976 to 2025
Uwem Okon Edet1,2,3, Md Zulfekar Ali4, Bassey Ini Ubi5
1Infectious & Transboundary Animal Diseases, National Veterinary Research Institute (NVRI), Vom, 930101, Nigeria, nvri.gov.ng.
Summary
Monkeypox virus (MPXV) research surged globally after the 2022 outbreak, led by the United States. Increased collaboration from MPXV-endemic regions is crucial for global preparedness.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Monkeypox virus (MPXV) research has intensified following the 2022 global outbreak.
- Despite MPXV's pandemic potential, a comprehensive overview of its global research landscape is lacking.
Purpose of the Study:
- To provide a holistic quantitative and qualitative analysis of the global MPXV research landscape.
- To identify trends, key players, and research priorities in MPXV studies.
Main Methods:
- Systematic literature review using the SPAR-4-SLR protocol on the Scopus database (1976-2025).
- Bibliometric analysis using Biblioshiny, RStudio, and VOSviewer.
- Screening and analysis of 5315 eligible records.
Main Results:
- MPXV research shows an average annual growth rate of 12.38%, with a significant increase post-2021.
- The United States leads in research output, funding, and collaboration, with the CDC as a key institution.
- Research focus shifted from virology to human transmission, epidemiology, vaccination, and therapeutics.
Conclusions:
- MPXV research expanded rapidly post-2021, primarily driven by high-income nations like the US.
- Enhanced research contributions, surveillance, and collaborations from MPXV-endemic African regions are vital for global health security.
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