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Rounded Monodisperse Fluorescent Nanodiamonds.

Helena Raabova¹, Ivan Rehor^1,2, Jan Havlik^1,2

¹Institute of Organic Chemistry and Biochemistry of the CAS, Prague, Czechia.

Small (Weinheim an Der Bergstrasse, Germany)

|May 27, 2026

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This summary is machine-generated.

Molten-nitrate etching and fractionation create uniform, rounded nanodiamonds. These enhanced nanodiamonds improve nitrogen-vacancy (NV) sensing and bioimaging applications.

Area of Science:

Materials Science
Nanotechnology
Quantum Sensing

Background:

High-pressure, high-temperature nanodiamonds (HPHT NDs) exhibit shape heterogeneity and surface sp² carbon.
These imperfections limit nitrogen-vacancy (NV) sensing and imaging capabilities.

Purpose of the Study:

To develop a scalable method for improving HPHT NDs for quantum sensing and bioimaging.
To round HPHT NDs and reduce surface sp² carbon content.

Main Methods:

Rapid molten-nitrate etching at 567°C for 6 minutes.
Centrifugal fractionation for size homogenization.
Characterization using TEM, HRTEM-EELS, and Raman spectroscopy.

Main Results:

Keywords:

etching monodisperse nanodiamond nitrogen‐vacancy center rounded

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Achieved particle circularity with reduced sp² carbon content.

Narrowed size distribution to a mean of 34 nm with reduced dispersity.

Enhanced photoluminescence and preserved NV properties after etching and annealing.

Conclusions:

Scalable molten-nitrate etching and fractionation yield shape-controlled, low-sp² nanodiamonds.
Improved nanodiamonds demonstrate enhanced optical properties for bioimaging and quantum sensing.
The process is compatible with scale-up, offering reproducible results.