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Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However, frequent irregular...
Ischemic Heart Disease: Overview01:17

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Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
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Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...

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Obstructive Sleep Apneas and Cardiovascular Diseases.

Vincenzo Castiglione1,2, Paolo Morfino1, Iacopo Fabiani1

  • 1Health Science Interdisciplinary Research Center, Scuola Superiore Sant'Anna, 56127 Pisa, Italy.

Clocks & Sleep
|May 27, 2026
PubMed
Summary
This summary is machine-generated.

Obstructive sleep apnea (OSA) is linked to heart disease. While treatments improve quality of life, evidence for reducing cardiovascular events is mixed, highlighting the need for better patient selection.

Keywords:
continuous positive airway pressureheart failureobesityobstructive sleep apnea

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Area of Science:

  • Cardiology
  • Sleep Medicine
  • Pulmonology

Background:

  • Obstructive sleep apnea (OSA) is a prevalent sleep-disordered breathing condition.
  • OSA involves recurrent upper-airway obstruction, leading to intermittent hypoxemia and sympathetic activation.
  • It is strongly associated with cardiovascular diseases, including hypertension, atrial fibrillation, and heart failure.

Purpose of the Study:

  • To review the pathophysiology of OSA and its cardiovascular consequences.
  • To summarize diagnostic and therapeutic strategies for OSA.
  • To highlight clinical implications for cardiology practice.

Main Methods:

  • Review of current evidence on OSA pathophysiology, cardiovascular effects, and treatments.
  • Discussion of established treatments: lifestyle changes, CPAP, mandibular devices, surgery.
  • Exploration of emerging therapies: pharmacological approaches for weight loss and ventilation.

Main Results:

  • OSA treatment improves patient symptoms and quality of life.
  • Evidence for reducing cardiovascular events with OSA treatment is heterogeneous.
  • Patient selection and treatment adherence significantly influence cardiovascular outcomes.

Conclusions:

  • Identifying patients who will benefit most from OSA management is crucial.
  • Further research is needed to optimize OSA treatment strategies for cardiovascular risk reduction.
  • Integrated care between sleep specialists and cardiologists is essential for managing OSA in cardiovascular patients.