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Related Concept Videos

Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Standard Precaution01:26

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

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Updated: May 28, 2026

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

A Risk-Based Isolation Strategy for MDR-Endemic Facilities with Limited Resources.

Zeynep Ture1, Emine Alp2,3

  • 1Department of Infectious Diseases, Gürlife Hospital, Eskişehir 26320, Türkiye.

Infectious Disease Reports
|May 27, 2026
PubMed
Summary
This summary is machine-generated.

Routine isolation for some multidrug-resistant organisms is unsustainable. A risk-based approach is needed, prioritizing containment for high-threat pathogens like CRE, CRAB, and Candida auris.

Keywords:
CREESBLRisk ClassificationVREcontact isolationinfection controlmultidrug resistance

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Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure

Published on: December 13, 2024

Area of Science:

  • Infectious Disease Epidemiology
  • Healthcare-Associated Infections
  • Microbiology

Background:

  • Rising prevalence of multidrug-resistant (MDR) microorganisms challenges healthcare resource allocation.
  • Traditional infection control strategies, including routine isolation of all carriers, are becoming unsustainable.
  • Limited resources in healthcare settings necessitate a reevaluation of current infection control practices.

Purpose of the Study:

  • To evaluate the sustainability of traditional infection control strategies in the context of increasing MDR organisms.
  • To synthesize a sustainable infection control strategy based on current evidence and international guidelines.
  • To propose a risk-based approach for prioritizing infection control measures.

Main Methods:

  • A clinical narrative review was performed using PubMed, Web of Science, and Google Scholar.
  • Literature search focused on studies published between 2011 and 2025.
  • Analysis of international guidelines to inform a sustainable infection control strategy.

Main Results:

  • Routine contact isolation for endemic ESBL-producing Enterobacterales and VRE offers no additional benefit over standard precautions.
  • Strict isolation is crucial for high-threat pathogens like Carbapenem-Resistant Enterobacterales (CRE), Acinetobacter baumannii (CRAB), and Candida auris.
  • Prioritization of isolation should consider pathogen biology, patient transmission traits, and facility infrastructure.

Conclusions:

  • A one-size-fits-all approach to infection control is unsustainable under resource constraints.
  • A risk-based strategy, prioritizing horizontal measures for low-risk pathogens, allows better resource allocation.
  • Focusing resources on high-threat pathogen containment is essential for effective infection control.