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How green are large language models for radiology report labelling? Comparing human, rule-based and hybrid workflows.
Matthias A Fink1,2, Arved Bischoff3, Edem Atsiatorme3
1Clinic for Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany. matthias.fink@uni-heidelberg.de.
Insights Into Imaging
|May 27, 2026
Summary
A hybrid rule-based-large language model (LLM) workflow significantly reduces time, cost, and carbon emissions for labelling CT pulmonary embolism reports compared to manual methods. This approach optimizes LLM deployment for sustainable radiology data annotation.
Area of Science:
- Radiology and Medical Imaging
- Artificial Intelligence in Healthcare
- Computational Linguistics
Background:
- Quantitative data on the sustainable use of large language models (LLMs) in radiology is limited.
- Manual labelling of radiology reports is resource-intensive, involving significant time and cost.
- Developing efficient and sustainable data annotation workflows is crucial for AI implementation in healthcare.
Purpose of the Study:
- To quantify the resource footprint (time, cost, carbon emissions) of LLMs for labelling CT pulmonary embolism (PE) reports.
- To compare a hybrid rule-based-LLM workflow against manual labelling and LLM-only approaches.
- To identify sustainable deployment strategies for LLMs in routine radiology reporting.
Main Methods:
- A retrospective study involving 2923 structured CT reports.
- Four labelling workflows were evaluated: rule-based extractor (RBE), LLM-only, hybrid RBE-LLM, and manual labelling.
- Resource metrics (latency, cost, CO2 emissions) were measured for LLMs; labelling time was recorded by radiologists.
Main Results:
- Manual labelling required 32.8 hours and cost €0.42/report with 95.0% accuracy.
- LLM-only pipelines reduced time and cost but had lower accuracy (85.1%).
- The hybrid RBE-LLM workflow achieved the highest accuracy (98.5%) while significantly reducing time (0.97 hours), cost (€0.17), and CO2 emissions (0.12 kg) compared to LLM-only and manual methods.
Conclusions:
- LLM-only labelling offers reduced labor time and direct costs but compromises accuracy.
- A hybrid RBE-LLM approach sustains high accuracy while minimizing resource consumption.
- This hybrid workflow enables targeted LLM deployment, supporting sustainable data annotation in radiology.