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Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
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Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

HIV/AIDS burden, attributable risk factors, and projections among reproductive-age adults in China, 1990-2035: A GBD

Huibo Yan1

  • 1Clinical Laboratory, Shanghai Putuo District Maternity and Infant Hospital, Shanghai, China.

Plos One
|May 27, 2026
PubMed

Insights

China

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • HIV/AIDS remains a significant global health challenge.
  • Antiretroviral therapy has made HIV a manageable chronic condition.
  • Understanding current HIV/AIDS trends in Chinese reproductive-age adults is crucial for epidemic control.

Purpose of the Study:

  • To provide an updated, comprehensive assessment of the HIV/AIDS burden in Chinese reproductive-age adults.
  • To analyze contemporary trends and identify attributable risk factors.
  • To forecast future HIV/AIDS burden using refined methodologies and post-pandemic data.

Main Methods:

  • Extracted age-standardized incidence, prevalence, mortality, and DALYs from GBD 2023 for Chinese adults (15-49 years).
  • Utilized Joinpoint regression for trend analysis and ARIMA models for forecasting to 2035.
  • Analyzed population attributable fractions for unsafe sex, drug use, and intimate-partner violence.

Main Results:

  • Between 1990-2023, age-standardized HIV/AIDS rates increased significantly across all metrics, with males showing steeper rises.
  • Unsafe sex was the primary contributor to HIV/AIDS mortality (70% in 2023).
  • Projections indicate continued female metric increases and widening sex disparities by 2035.

Conclusions:

  • China's HIV epidemic is now a chronic disease burden with significant sex differences.
  • Rising mortality, particularly among women, necessitates gender-differentiated prevention strategies.
  • Findings support China's National HIV/AIDS Action Plan and SDG 3.3 monitoring.
Abstract

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