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Reimagining Orthopaedic Research: The Musculoskeletal Adaptive Platform Trial (MAPT) Design Rationale
Nathan N O'Hara1, Sheila A Sprague2,3,4, Joseph P Patterson5
1Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland.
Abstract
Clinical Relevance:
The MAPT is clinically relevant because it provides a practical framework for rapidly identifying which treatments improve survival, mobility, and recovery in patients with musculoskeletal conditions. It can directly guide better treatment decisions regarding a leading cause of disability.